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The Expansion Phase of Phase I Oncology Trials
The Expansion Phase of Phase I Oncology Trials

Phase 1A/1B dose-escalation and -expansion study to evaluate the safety,  pharmacokinetics, food effects and antitumor activity of pamiparib in  advanced solid tumours | British Journal of Cancer
Phase 1A/1B dose-escalation and -expansion study to evaluate the safety, pharmacokinetics, food effects and antitumor activity of pamiparib in advanced solid tumours | British Journal of Cancer

Mesenchymal Stem Cells for Bronchopulmonary Dysplasia: Phase 1 Dose- Escalation Clinical Trial - The Journal of Pediatrics
Mesenchymal Stem Cells for Bronchopulmonary Dysplasia: Phase 1 Dose- Escalation Clinical Trial - The Journal of Pediatrics

Dose-finding trials: why not to use algorithmic designs
Dose-finding trials: why not to use algorithmic designs

توییتر \ Stephen V Liu, MD در توییتر: «#OncoAlert #AACR20 Dose escalation  of TAK-788 (mobocertinib) established MTD of 160mg qday. DLTs were 1 case  each of grade 3 diarrhea, grade 3 mucositis,
توییتر \ Stephen V Liu, MD در توییتر: «#OncoAlert #AACR20 Dose escalation of TAK-788 (mobocertinib) established MTD of 160mg qday. DLTs were 1 case each of grade 3 diarrhea, grade 3 mucositis,

Dose Escalation and Co-therapy Intensification Between Etanercept,  Adalimumab, and Infliximab: The CADURA Study
Dose Escalation and Co-therapy Intensification Between Etanercept, Adalimumab, and Infliximab: The CADURA Study

Dose intra‐subject escalation to an event (DIETE): A new method for phase 1  dose‐finding utilizing systematic intra‐subject dose escalation with  application to T‐cell engagers - Xu - 2021 - Pharmaceutical Statistics -
Dose intra‐subject escalation to an event (DIETE): A new method for phase 1 dose‐finding utilizing systematic intra‐subject dose escalation with application to T‐cell engagers - Xu - 2021 - Pharmaceutical Statistics -

Inter-patient and intra-patient dose escalation strategy. Patients were...  | Download Scientific Diagram
Inter-patient and intra-patient dose escalation strategy. Patients were... | Download Scientific Diagram

Ustekinumab dose escalation: An option for nonresponsive Crohn's? | Latest  news for Doctors, Nurses and Pharmacists | Pharmacy
Ustekinumab dose escalation: An option for nonresponsive Crohn's? | Latest news for Doctors, Nurses and Pharmacists | Pharmacy

Sequential dose-escalation study design | Download Scientific Diagram
Sequential dose-escalation study design | Download Scientific Diagram

Immune checkpoint inhibitor-based combinations: is dose escalation  mandatory for phase I trials? - Annals of Oncology
Immune checkpoint inhibitor-based combinations: is dose escalation mandatory for phase I trials? - Annals of Oncology

JCI Insight - First-in-human trial of multikinase VEGF inhibitor  regorafenib and anti-EGFR antibody cetuximab in advanced cancer patients
JCI Insight - First-in-human trial of multikinase VEGF inhibitor regorafenib and anti-EGFR antibody cetuximab in advanced cancer patients

Protocol B7861002 A PHASE 1 DOSE ESCALATION STUDY TO EVALUATE THE SAFETY,  PHARMACOKINETICS AND PHARMACODYNAMICS OF INTRAVENOUS P
Protocol B7861002 A PHASE 1 DOSE ESCALATION STUDY TO EVALUATE THE SAFETY, PHARMACOKINETICS AND PHARMACODYNAMICS OF INTRAVENOUS P

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PDF] Dose Escalation Methods in Phase I Cancer Clinical Trials | Semantic  Scholar
PDF] Dose Escalation Methods in Phase I Cancer Clinical Trials | Semantic Scholar

A phase Ib dose-escalation study of erlotinib, capecitabine and oxaliplatin  in metastatic colorectal cancer patients - Annals of Oncology
A phase Ib dose-escalation study of erlotinib, capecitabine and oxaliplatin in metastatic colorectal cancer patients - Annals of Oncology

Phase I/II study of oxaliplatin dose escalation via a laparoscopic approach  using pressurized aerosol intraperitoneal chemotherapy (PIPOX trial) for  nonresectable peritoneal metastases of digestive cancers (stomach, small  bowel and colorectal ...
Phase I/II study of oxaliplatin dose escalation via a laparoscopic approach using pressurized aerosol intraperitoneal chemotherapy (PIPOX trial) for nonresectable peritoneal metastases of digestive cancers (stomach, small bowel and colorectal ...

A Phase 1 Randomized Dose-Escalation Study of a Human Monoclonal Antibody  to IL-6 in CKD | American Society of Nephrology
A Phase 1 Randomized Dose-Escalation Study of a Human Monoclonal Antibody to IL-6 in CKD | American Society of Nephrology

5 Reasons to Invest in Bayesian Dose-Escalation Methods
5 Reasons to Invest in Bayesian Dose-Escalation Methods

Nivolumab in patients with advanced hepatocellular carcinoma (CheckMate  040): an open-label, non-comparative, phase 1/2 dose escalation and  expansion trial - The Lancet
Nivolumab in patients with advanced hepatocellular carcinoma (CheckMate 040): an open-label, non-comparative, phase 1/2 dose escalation and expansion trial - The Lancet

Dose escalation. The dose escalation was performed in both intra and... |  Download Scientific Diagram
Dose escalation. The dose escalation was performed in both intra and... | Download Scientific Diagram

Flexibility of the BLRM in Dose-Escalation Trials
Flexibility of the BLRM in Dose-Escalation Trials

Contemporary dose-escalation methods for early phase studies in the  immunotherapeutics era - ScienceDirect
Contemporary dose-escalation methods for early phase studies in the immunotherapeutics era - ScienceDirect

Phase I/II Dose-Escalation Trial of Daratumumab for Relapsed/Refractory  Multiple Myeloma | Research To Practice
Phase I/II Dose-Escalation Trial of Daratumumab for Relapsed/Refractory Multiple Myeloma | Research To Practice

Early phase clinical trials to identify optimal dosing and safety -  ScienceDirect
Early phase clinical trials to identify optimal dosing and safety - ScienceDirect

Contemporary dose-escalation methods for early phase studies in the  immunotherapeutics era - European Journal of Cancer
Contemporary dose-escalation methods for early phase studies in the immunotherapeutics era - European Journal of Cancer