![Ketamine—50 years in use: from anesthesia to rapid antidepressant effects and neurobiological mechanisms | SpringerLink Ketamine—50 years in use: from anesthesia to rapid antidepressant effects and neurobiological mechanisms | SpringerLink](https://media.springernature.com/lw685/springer-static/image/art%3A10.1007%2Fs43440-021-00232-4/MediaObjects/43440_2021_232_Fig2_HTML.png)
Ketamine—50 years in use: from anesthesia to rapid antidepressant effects and neurobiological mechanisms | SpringerLink
![Ketamine Works as a Fast-Acting Antidepressant, But the Full Effects Are Still Unknown | Science| Smithsonian Magazine Ketamine Works as a Fast-Acting Antidepressant, But the Full Effects Are Still Unknown | Science| Smithsonian Magazine](https://th-thumbnailer.cdn-si-edu.com/FcMQl0ear61UR7D2jHFOB0-zBkQ=/fit-in/1600x0/https://tf-cmsv2-smithsonianmag-media.s3.amazonaws.com/filer/f2/3b/f23ba372-83cb-4fb8-a134-90dfe4688f49/mr8hwp.jpg)
Ketamine Works as a Fast-Acting Antidepressant, But the Full Effects Are Still Unknown | Science| Smithsonian Magazine
![A higher dose (0.8 mg/kg) of ketamine infusion for treatment-resistant depression: An open-label study in Taiwan Chen MH, Lin WC, Li CT, Su TP - Taiwan J Psychiatry A higher dose (0.8 mg/kg) of ketamine infusion for treatment-resistant depression: An open-label study in Taiwan Chen MH, Lin WC, Li CT, Su TP - Taiwan J Psychiatry](https://www.e-tjp.org/articles/2020/34/2/images/TaiwanJPsychiatry_2020_34_2_72_288010_t5.jpg)
A higher dose (0.8 mg/kg) of ketamine infusion for treatment-resistant depression: An open-label study in Taiwan Chen MH, Lin WC, Li CT, Su TP - Taiwan J Psychiatry
![Identification of an optimal dose of intravenous ketamine for late-life treatment-resistant depression: a Bayesian adaptive randomization trial | Neuropsychopharmacology Identification of an optimal dose of intravenous ketamine for late-life treatment-resistant depression: a Bayesian adaptive randomization trial | Neuropsychopharmacology](https://media.springernature.com/full/springer-static/image/art%3A10.1038%2Fs41386-021-01242-9/MediaObjects/41386_2021_1242_Fig1_HTML.png)
Identification of an optimal dose of intravenous ketamine for late-life treatment-resistant depression: a Bayesian adaptive randomization trial | Neuropsychopharmacology
![Convergent theory of ketamine's mechanism of action in depression. 1)... | Download Scientific Diagram Convergent theory of ketamine's mechanism of action in depression. 1)... | Download Scientific Diagram](https://www.researchgate.net/publication/314080636/figure/fig1/AS:493088369057792@1494572836384/Convergent-theory-of-ketamines-mechanism-of-action-in-depression-1-At-low-doses.png)
Convergent theory of ketamine's mechanism of action in depression. 1)... | Download Scientific Diagram
Antidepressant Actions of Ketamine: Potential Role of L-Type Calcium Channels | Chemical Research in Toxicology
![The Sustained Antidepressant Effects of Ketamine Are Independent of the Lateral Habenula | Journal of Neuroscience The Sustained Antidepressant Effects of Ketamine Are Independent of the Lateral Habenula | Journal of Neuroscience](https://www.jneurosci.org/content/jneuro/41/18/4131/F1.large.jpg)
The Sustained Antidepressant Effects of Ketamine Are Independent of the Lateral Habenula | Journal of Neuroscience
![A Double-Blind, Randomized, Placebo-Controlled, Dose-Frequency Study of Intravenous Ketamine in Patients With Treatment-Resistant Depression | American Journal of Psychiatry A Double-Blind, Randomized, Placebo-Controlled, Dose-Frequency Study of Intravenous Ketamine in Patients With Treatment-Resistant Depression | American Journal of Psychiatry](https://ajp.psychiatryonline.org/cms/10.1176/appi.ajp.2016.16010037/asset/images/medium/appi.ajp.2016.16010037f2.gif)
A Double-Blind, Randomized, Placebo-Controlled, Dose-Frequency Study of Intravenous Ketamine in Patients With Treatment-Resistant Depression | American Journal of Psychiatry
![Dose-related effects of ketamine for antidepressant-resistant symptoms of posttraumatic stress disorder in veterans and active duty military: a double-blind, randomized, placebo-controlled multi-center clinical trial | Neuropsychopharmacology Dose-related effects of ketamine for antidepressant-resistant symptoms of posttraumatic stress disorder in veterans and active duty military: a double-blind, randomized, placebo-controlled multi-center clinical trial | Neuropsychopharmacology](https://media.springernature.com/full/springer-static/image/art%3A10.1038%2Fs41386-022-01266-9/MediaObjects/41386_2022_1266_Fig1_HTML.png)
Dose-related effects of ketamine for antidepressant-resistant symptoms of posttraumatic stress disorder in veterans and active duty military: a double-blind, randomized, placebo-controlled multi-center clinical trial | Neuropsychopharmacology
![Antidepressant-relevant concentrations of the ketamine metabolite (2R,6R)-hydroxynorketamine do not block NMDA receptor function | PNAS Antidepressant-relevant concentrations of the ketamine metabolite (2R,6R)-hydroxynorketamine do not block NMDA receptor function | PNAS](https://www.pnas.org/cms/10.1073/pnas.1816071116/asset/4fcbde8a-6e7c-47b6-b19d-6cb3b5a591dc/assets/graphic/pnas.1816071116fig03.jpeg)
Antidepressant-relevant concentrations of the ketamine metabolite (2R,6R)-hydroxynorketamine do not block NMDA receptor function | PNAS
![Single sub-anesthetic dose of ketamine (20 mg/kg) relieved CPSP-related... | Download Scientific Diagram Single sub-anesthetic dose of ketamine (20 mg/kg) relieved CPSP-related... | Download Scientific Diagram](https://www.researchgate.net/publication/339661295/figure/fig3/AS:941385167413272@1601455122641/Single-sub-anesthetic-dose-of-ketamine-20mg-kg-relieved-CPSP-related-depression-in-rats.png)